Last night at about 20:05, Netcare911 paramedics were called to a scene where a bakkie collided with a light motor vehicle on the N1 near Buccleuch, Sandton.
The exact detail to the cause of the crash will remain a subject for police investigation and comment.
Reports from the scene indicate that eleven people sustained injuries varying from serious to moderate.
The Netcare1 helicopter was dispatched to the scene to airlift a critically injured person to a Johannesburg hospital for further medical care.
The other ten people who were injured were transported by ambulance to a nearby hospital for further medical care.
Netcare911 paramedics worked alongside other services on scene to treat the injured.